Membrane Array Analysis of Tear Proteins in Ocular Cicatricial Pemphigoid
نویسندگان
چکیده
منابع مشابه
Ocular Cicatricial Pemphigoid
CC (6/20/96): Red, itchy eyes, whitish discharge x 6 weeks HPI: A 74 year old retired policeman noticed red, itchy eyes associated with whitish discharge that worsened over the past six weeks. Two weeks later, the patient consulted his ophthalmologist, who treated him antibiotic eye drops without a favorable response. The patient did not respond to the antibiotic and states he was biopsied. He ...
متن کاملEosinophil granule proteins expressed in ocular cicatricial pemphigoid.
BACKGROUND Blister formation and tissue damage in bullous pemphigoid have been attributed to the release of eosinophil granule proteins--namely, to eosinophil derived cationic protein (ECP) and major basic protein (MBP). In the present investigation these eosinophil granule proteins were studied in the conjunctiva of patients with ocular cicatricial pemphigoid (OCP). METHODS Conjunctival biop...
متن کاملProgression of disease in ocular cicatricial pemphigoid.
BACKGROUND Ocular cicatricial pemphigoid (OCP) is a sight threatening autoimmune disease that can lead to severe conjunctival cicatrisation and keratopathy. It has a variable course and little is known about the factors that determine disease progression. This study analysed the factors that have prognostic significance regarding disease outcome, progression, and keratopathy. METHODS Sixty si...
متن کاملCataract surgery in ocular cicatricial pemphigoid.
The authors report the results of their experience with cataract surgery in 20 patients (26 eyes) with biopsy-proven cicatricial pemphigoid. All patients were on systemic immunosuppression at the time of surgery (dapsone, azathioprine, cyclophosphamide, or combinations) and were treated with perioperative oral corticosteroids. Patients were evaluated pre- and postoperatively for conjunctival in...
متن کاملOcular involvement in anti-epiligrin cicatricial pemphigoid.
PURPOSE To report an anti-epiligrin cicatricial pemphigoid (AECP) patient with severe ocular involvement and to provide a practical approach to distinguishing AECP patients from those with other subepidermal blistering diseases. METHODS Techniques included direct and indirect immunofluorescence microscopy, Western blot and immunoprecipitation studies, as well as interdisciplinary examinations...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Optometry and Vision Science
سال: 2011
ISSN: 1040-5488
DOI: 10.1097/opx.0b013e31821ddc6c